Generic Substitutions for Antiepileptic Drugs
نویسندگان
چکیده
منابع مشابه
Antiepileptic drugs: the drawbacks of generic substitution.
The need to curb the rising costs of health care has led policy-makers in many countries to consider widespread generic substitution of brand-name drugs as an eff ective means to cut costs. For example, on January 5, 2010, the NHS in England began a 3-month consultation to seek views on plans to automatically substitute branded drugs with generic versions in primary care. However, doctors, pati...
متن کاملGeneric antiepileptic drugs: how good is close enough?
Commentary It used to be that cost was only one of the many factors that played into the therapeutic decision-making process. That was then, and this is now. Now, for many individuals, cost is the primary factor governing choice of drug treatment. There are many reasons why a patient might fail to achieve optimal seizure control, including such things as drug interactions, treatment emergent ad...
متن کاملGeneric substitution of antiepileptic drugs: What's a clinician to do?
Generic substitution of antiepileptic drugs remains a controversial area without a clear consensus to guide clinicians. The US Food and Drug Administration (FDA) requires rigorous testing of generic products and states that all approved products are interchangeable. FDA studies involve single doses in normal subjects so may not represent the performance of generic products in people with epilep...
متن کاملBrand spanking? The presumptive risks of generic antiepileptic drugs.
Commentary In a room full of epilepsy physicians—or their patients—the one topic most likely to cause the proverbial excrement to strike the rotating blades is that of generic antiepileptic drugs (AEDs). Passions run high, with those at one end of the worry spectrum convinced that the widespread use of generics poses a primordial threat to the well-being of patients with seizures, while those a...
متن کاملTherapeutic equivalency of generic antiepileptic drugs: results of a survey.
Controversy persists whether generic antiepileptic drugs (AEDs) are interchangeable with brand name drugs with respect to efficacy and adverse events. Three hundred and one neurologists responded to a survey regarding generic AEDs mailed to 6420 neurologists, for an overall response rate of 4.7%. One hundred and ninety-six (67.8%) neurologists reported breakthrough seizures after a switch from ...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1990
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-4-11-9